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VCU Pauley Heart Center, VCU Medical Center, Virginia Commonwealth University VCU Pauley Heart Center VCU Medical Center VCU

VCU Pauley Heart Center

Physicians and staff

Fadi Salloum, PhDFadi N. Salloum, Ph.D., F.A.H.A.


A native of Beirut, Lebanon, Dr. Salloum earned his BS in Biology from the American University of Beirut in 1996. After graduation he served his military service in the Lebanese Army Medical Brigade.

Dr. Salloum immigrated to the United States in 1998 to pursue his Doctorate in Physiology from Virginia Commonwealth University School of Medicine. He completed his postdoctoral training in “Novel Cardioprotective Strategies against Ischemia/Reperfusion Injury” in 2008 under the mentorship of Dr. Rakesh C. Kukreja, director of the Molecular Cardiology Research Laboratories at the VCU Pauley Heart Center. He was appointed as Assistant Professor of Medicine in January of 2009. He also holds an affiliate Assistant Professorship in the department of Physiology & Biophysics at VCU School of Medicine.

Dr. Salloum’s investigative skills were recognized very early in his career with the American Heart Association Young Investigator Award; the Elizabeth Fries Young Investigator Award, Clinical Honorable Mention; and the American Association for the Advancement of Science, Excellence in Science Award.

As a talented and inspiring educator, he has participated in several courses offered to physiology graduate students, dental students, as well as physiology labs to first year medical students. Recently, he assumed the position of course director of a PHIS 512: “Cardiac Function in Health and Disease”, which is offered by the physiology department to graduate students. This course is distinguished by its clinical focus on a variety of cardiac diseases. He has also been involved in the basic research training of numerous undergraduate and graduate students as well as cardiology fellow trainees.

Dr. Salloum’s current research is focused on myocardial ischemia-reperfusion injury and heart failure. His major interest is developing novel pharmacologic strategies to combat cardiovascular disease and heart failure. His research is directed towards identifying the role of the novel gasotransmitter, hydrogen sulfide (H2S), in cardioprotection against ischemia. This also includes investigations involving phosphodiesterase type 5 inhibitors and microRNAs (miRs) and their roles in cardioprotection. As a principal investigator, Dr. Salloum is currently funded by a Grant in Aid from the American Heart Association for his research on H2S and an Investigator Initiated Research Proposal from Novartis Foundation to study the benefits of serelaxin in acute ischemic heart failure. Dr. Salloum was previously funded by a National Scientist Development Grant from the American Heart Association (2010 – 2014) and a VCU Presidential Incentive Research Program (PRIP) grant.

Dr. Salloum serves as grant reviewer for the American Heart Association – Cardiac Biology Regulation Study Group, the National Science Foundation (ad hoc) as well as international funding organizations for cardiovascular research.

Dr. Salloum is also a principal investigator on a clinical research project involving evaluation of apoptosis, or programmed cell death, in patients with heart failure due to different causes, and co-investigator on another clinical research project involving prevention of post-infarction adverse remodeling in patients.
            Dr. Salloum is a Fellow of the American Heart Association- Council on Basic Cardiovascular Sciences; and a member of the American Physiological Society- Cardiovascular Section; the International Society for Heart Research; and the American Society of Echocardiography.

He has authored or co-authored more than 70 articles that have been published in high quality peer-reviewed biomedical journals such as Circulation, Circulation Research, Journal of the American College of Cardiology, Proceedings of the National Academy of Science, Journal of Molecular and Cellular Cardiology, Molecular Pharmacology, Journal of Biological Chemistry, the American Journal of Physiology Heart and Circulatory Physiology, and several others. Additionally, he has authored or co-authored 3 book chapters, more than 100 abstracts and made numerous presentations at the American Heart Association and American College of Cardiology scientific meetings.

Dr. Salloum was appointed to the Editorial Board of PLoS One as an Academic Editor in 2011, the Editorial Board of Scientifica in 2012 and joined the Editorial Board of the American Journal of Cardiology in 2014. Dr. Salloum has served as reviewer for numerous national and international biomedical journals, which include: Journal of the American College of Cardiology, Circulation, European Heart Journal, Circulation – Heart Failure, Journal of Molecular and Cellular Cardiology, American Journal of Cardiology, American Journal of Physiology, European Journal of Heart Failure, Canadian Journal of Physiology and Pharmacology, International Journal of Cardiology, PLoS One (Public Library of Science), Cardiovascular Drugs and Therapy, Life Sciences, European Surgical Research, Journal of Urology, International Journal of Biological Sciences, International Journal of Molecular Sciences, Acta Biochimica et Biophysica Sinica, and Scientifica.



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